The FIAflex Microalbumin FIA 25 Test is a fluorescence immunoassay designed for the quantitative detection of microalbumin (a small blood protein) in human urine. It is used as a screening tool for early kidney disease, especially in people with diabetes or high blood pressure. The "25 Test" indicates the number of tests in the kit.
Key features
Technology: The FIAflex system uses a Time-resolved Fluorescence Immunoassay (TR-FIA) methodology, which utilizes Europium ions to create a stable fluorescent signal. This technique significantly reduces background noise, resulting in a more sensitive and accurate assay compared to conventional fluorescent methods.
Quantitative results: Unlike simple qualitative tests that only show a positive or negative result, this test provides a precise measurement of the microalbumin concentration.
Rapid testing: The test can provide results in as little as 10 to 12 minutes, offering a quick turnaround for diagnostic purposes.
Automated analysis: The FIAflex test system typically uses a dedicated analyzer to read the fluorescent signal and calculate the final result.
Intended use and purpose
The test is an in vitro diagnostic tool used to screen for early signs of kidney damage. Normally, healthy kidneys prevent albumin from entering the urine. The persistent appearance of small amounts of albumin is an early indicator of impaired kidney function, or microalbuminuria.
The test is important for:
Diabetes management: The American Diabetes Association recommends annual microalbumin screening for people with diabetes, as it is the most common cause of kidney failure.
High blood pressure monitoring: Hypertension can also damage kidney vessels and cause albumin to leak into the urine.
Cardiovascular risk assessment: Microalbuminuria is considered an independent risk factor for cardiovascular disease.
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